
Lexapro (Escitalopram) |
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Lexapro (Escitalopram) is used for treating depression and anxiety. Lexapro is a convenient, once-daily pill for major depressive disorder (MDD) and generalized anxiety disorder (GAD). Lexapro is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). It affects chemicals in the brain that may become unbalanced and cause depression or anxiety. Lexapro is used for treating depression and anxiety. It may also be used for other conditions as determined by your doctor. Lexapro (escitalopram oxalate) is an orally administered selective serotonin reuptake inhibitor . Escitalopram is the pure S-enantiomer (single isomer) of the racemic bicyclic phthalane derivative citalopram. Escitalopram oxalate is designated S-(+)-1-[3-(dimethyl-amino)propyl]-1-(pfluorophenyl)-5-phthalancarbonitrile oxalate with the following molecular formula is C20H21FN2OoC2H2O4 and the molecular weight is 414.40. Escitalopram oxalate occurs as a fine, white to slightly-yellow powder and is freely soluble in methanol and dimethyl sulfoxide (DMSO), soluble in isotonic saline solution, sparingly soluble in water and ethanol, slightly soluble in ethyl acetate, and insoluble in heptane.Lexapro (escitalopram oxalate) is available as tablets or as an oral solution.Lexapro oral solution contains escitalopram oxalate equivalent to 1 mg/mL escitalopram base. It also contains the following inactive ingredients: sorbitol, purified water, citric acid, sodium citrate, malic acid, glycerin, propylene glycol, methylparaben, propylparaben, and natural peppermint flavor. Drug Class Lexapro (Escitalopram) is not a controlled substance. Animal studies suggest that the abuse liability of racemic citalopram is low. Lexapro has not been systematically studied in humans for its potential for abuse, tolerance, or physical dependence. The premarketing clinical experience with Lexapro did not reveal any drug-seeking behavior. Consequently, physicians should carefully evaluate Lexapro patients for history of drug abuse and follow such patients closely, observing them for signs of misuse or abuse (e.g., development of tolerance, incrementations of dose, drug-seeking behavior). Lexapro (Escitalopram) is a selective serotonin reuptake inhibitor (SSRI) type of antidepressant. It works by increasing the activity of a chemical in the brain called serotonin, which helps to elevate mood. Lexapro works by helping to restore the balance of certain natural chemicals in the brain (neurotransmitters). Escitalopram is available with a prescription under the brand name Lexapro. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you. Lexapro 5 mg - white, round, tablets White to off-white, round, non-scored, film-coated. Imprint "FL" on one side of the tablet and "5" on the other side. Lexapro 10 mg - white, round, scored tablets White to off-white, round, scored, film-coated. Imprint on scored side with "F" on the left side and "L" on the right side. Imprint on the non-scored side with "10". Lexapro 20 mg - white, round, scored tablets White to off-white, round, scored, film-coated. Imprint on scored side with "F" on the left side and "L" on the right side. Imprint on the non-scored side with "20". Lexapro 5 mg/5 mL - peppermint flavor (240 mL)-flavored oral solution Drug Uses Lexapro (Escitalopram) is used to treat anxiety and major depressive disorder. Escitalopram is a selective serotonin reuptake inhibitor (SSRI) used to treat depression and generalized anxiety disorder. Lexapro may also be used for purposes other than those listed in this medication guide Important information about Lexapro Tell your doctor immediately if you have any suicidal thoughts, worsening depression, or any other mental/mood changes (including new or worsening anxiety, agitation, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, rapid speech). Tell your doctor your medical history, especially of: liver problems, kidney problems, seizures, heart problems, other mental/mood disorders e.g., bipolar disorder, thyroid problems, mineral (electrolyte) problems e.g., hyponatremia, SIADH, any allergies. This drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. Though uncommon, depression can lead to thoughts or attempts of suicide. Keep all medical appointments so your healthcare professional can monitor your progress closely and adjust/change your medication if needed. Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug. SSRI antidepressants may cause serious or life-threatening lung problems in newborn babies whose mothers take the medication during pregnancy. However, you may have a relapse of depression if you stop taking your antidepressant during pregnancy. If you are planning a pregnancy, or if you become pregnant while taking Lexapro, do not stop taking the medication without first talking to your doctor. Lexapro is not approved for use in pediatric patients. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. If this medication is used during the last 3 months of pregnancy, infrequently your newborn may develop symptoms including feeding or breathing difficulties, seizures, muscle stiffness, jitteriness, or constant crying. However, do not stop taking this medication unless your doctor directs you to do so. Report any such symptoms to your doctor promptly. This drug passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding. Anyone considering the use of Lexapro or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Lexapro (escitalopram) is indicated for the treatment of major depressive disorder. The efficacy of Lexapro in the treatment of major depressive disorder was established in three, 8 week, placebo-controlled trials of outpatients whose diagnoses corresponded most closely to the DSM-IV category of major depressive disorder A major depressive episode (DSM-IV) implies a prominent and relatively persistent (nearly every day for at least 2 weeks) depressed or dysphoric mood that usually interferes with daily functioning, and includes at least five of the following nine symptoms: loss of interest in usual activities, depressed mood, significant change in weight and/or appetite, insomnia or hypersomnia, psychomotor agitation or retardation, feelings of guilt or worthlessness, increased fatigue, slowed thinking or impaired concentration, a suicide attempt or suicidal ideation. The efficacy of Lexapro in the long-term treatment of GAD, that is, for more than 8 weeks, has not been systematically evaluated in controlled trials. The physician who elects to use Lexapro (Escitalopram) for extended periods should periodically re-evaluate the long-term usefulness of the drug for the individual patient. How Taken Use Lexapro (Escitalopram) as directed by your doctor. Take this medication by mouth usually once daily with or without food; or as directed by your doctor. Take Lexapro exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Your doctor may occasionally change your dose to make sure you get the best results from the medication. Take each dose of Lexapro with a full glass of water. Try to take the medicine at the same time each day. Follow the directions on your prescription label. The recommended dose of Lexapro is 10 mg once daily. A fixed-dose trial of Lexapro (Escitalopram) demonstrated the effectiveness of both 10 mg and 20 mg of Lexapro, but failed to demonstrate a greater benefit of 20 mg over 10 mg. If the dose is increased to 20 mg, this should occur after a minimum of one week. Lexapro should be administered once daily, in the morning or evening, with or without food. If stomach upset occurs, take with food to reduce stomach irritation. 10 mg/day is the recommended dose for most elderly patients and patients with hepatic impairment. No dosage adjustment is necessary for patients with mild or moderate renal impairment. Lexapro should be used with caution in patients with severe renal impairment. To be sure you get the correct dose of liquid Lexapro, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. It may take 4 weeks or longer before you start feeling better. You may have unpleasant side effects if you stop taking this medication suddenly. You should take your dosage at the same time each day, either in the morning or in the evening. The dosage is based on your medical condition and response to therapy. Lexapro (Escitalopram) comes with an additional patient information sheet called a Medication Guide. Several weeks may pass before Lexapro reaches full effect. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased. It may take up to several weeks before the full benefit of this drug takes effect. It is important to continue taking this medication as prescribed even if you feel well. Do not stop taking this medication without consulting your doctor. Do not use Lexapro (Escitalopram) if you are using an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), rasagiline (Azilect), or selegiline (Eldepryl, Emsam). Serious and sometimes fatal reactions can occur when these medicines are taken with Lexapro. You must wait at least 14 days after stopping an MAO inhibitor before you can take Lexapro. After you stop taking Lexapro, you must wait at least 14 days before you start taking an MAOI. Symptoms associated with discontinuation of Lexapro and other SSRIs and SNRIs have been reported. Patients should be monitored for these symptoms when discontinuing treatment. A gradual reduction in the dose rather than abrupt cessation is recommended whenever possible. If intolerable symptoms occur following a decrease in the dose or upon discontinuation of treatment, then resuming the previously prescribed dose may be considered. Subsequently, the physician may continue decreasing the dose but at a more gradual rate. Do not give Lexapro to anyone younger than 18 years old without the advice of a doctor. Missed Dose If you miss a dose of Lexapro (Escitalopram), take it as soon as possible. If it is near the time of the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose to catch up. overdose If overdose is suspected, contact your local poison control center or emergency room immediately. Overdose symptoms may include nausea, vomiting, tremor, sweating, rapid heartbeat, confusion, dizziness, seizures, and coma. Lexapro side effects. Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes aspirin and NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others. Taking any of these drugs with escitalopram may cause you to bruise or bleed easily. Avoid drinking alcohol, which can increase some of the side effects of Lexapro. Lexapro (Escitalopram) can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures or anxiety). They can add to sleepiness caused by Lexapro. Get emergency medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have any of these serious side effects: seizure (convulsions); tremors, shivering, muscle stiffness or twitching problems with balance or coordination; or agitation, confusion, sweating, fast heartbeat Less serious Lexapro side effects may include: feeling nervous, restless, or unable to sit still drowsiness, dizziness nausea, diarrhea, heartburn, constipation dry mouth, ringing in your ears. headache, trouble concentrating sleep problems (insomnia), loss of appetite weight changes decreased sex drive, impotence, or difficulty having an orgasm stomach pain fatigue, increased sweating, or dry mouth may occur. unusual or severe mental/mood changes. black stools, "coffee ground" vomit, easy bruising/bleeding Males - If you experience a painful and prolonged erection, stop using this drug and seek immediate medical attention. (Although changes in sexual desire, sexual performance, and sexual satisfaction often occur as manifestations of a psychiatric disorder, they may also be a consequence of pharmacologic treatment. In particular, some evidence suggests that SSRIs can cause such untoward sexual experiences.) This is not a complete list of side effects and others may occur. An allergic reaction to this drug is unlikely. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. Tell your doctor about any unusual or bothersome side effect. Adverse events that were associated with the discontinuation of at least 1% of patients treated with Lexapro, and for which the rate was at least twice that of placebo, were nausea (2%) and ejaculation disorder (2% of male patients). Among the 429 GAD patients who received Lexapro 10-20 mg/day in placebo-controlled trials, 8% discontinued treatment due to an adverse event, as compared to 4% of 427 patients receiving placebo. Adverse events that were associated with the discontinuation of at least 1% of patients treated with Lexapro, and for which the rate was at least twice the placebo rate, were nausea (2%), insomnia (1%), and fatigue (1%). DRUG INTERACTIONS: Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine) within 2 weeks before or after treatment with this medication. Consult your doctor or pharmacist for additional information. Do not take this medication with citalopram because the two agents are very similar. Ask your doctor or pharmacist for more details. This drug should not be used with the following medications because very serious interactions may occur: weight loss drugs (e.g., sibutramine, phentermine). This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others. Taking any of these drugs with Lexapro may cause you to bruise or bleed easily. Before taking Lexapro, tell your doctor if you are using any of the following medicines: carbamazepine (Carbatrol, Tegretol); cimetidine (Tagamet); lithium (Lithobid, Eskalith); a blood thinner such as warfarin (Coumadin); any other antidepressants such as amitriptyline (Elavil), citalopram (Celexa), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), or sertraline (Zoloft); or almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig). If you are using any of these drugs, you may not be able to use Lexapro, or you may need dosage adjustments or special tests during treatment. There may be other drugs not listed that can affect Lexapro (Escitalopram). Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Tell your doctor of all prescription and without prescription medication you may use Low-dose aspirin (usually 81-325 mg per day) for heart attack or stroke prevention should be continued unless your doctor instructs you otherwise. Aspirin is similar to NSAID drugs, and can increase the risk of bleeding in combination with this medication (see above). Discuss the risks and benefits with your doctor. Tell your doctor if you take any drugs that cause drowsiness such as: medicine for sleep (e.g., sedatives), tranquilizers, anti-anxiety drugs (e.g., diazepam), narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., phenothiazines such as chlorpromazine), anti-seizure drugs (e.g., phenytoin), muscle relaxants, antihistamines that cause drowsiness (e.g., diphenhydramine). Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products. Do not start or stop any medicine without doctor or pharmacist approval. Storage Store Lexapro (Escitalopram) at 25°C (77°F). Store away from heat, moisture, and light. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not store in the bathroom. Keep this and all other medicines out of the reach of children, never share your medicines with others, and only use this medication for the indication prescribed. You can order Lexapro(Escitalopram) online without prescriptions now from this site. You can order Antabuse (Disulfiram) online without prescriptions now from this site. |
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